This lectures for these objectives occurred on 8/27, 8/30, 8/31, and 9/1.
Link to HandoutsEdit
Link to PanoptoEdit
- 8/27 - Antihistamines
- 8/30 - Antihistamines
- 8/31 - 2nd Gen Antihistamines & H2 Blockers
- 9/1 - H2 blockers
Edited by Coastermonger 20:24, September 23, 2010 (UTC)
Describe how histamine is synthesized in vivo.Edit
Histamine is synthesized from Histidine via the enzyme Histidine Decarboxylase (HDC). The molecule is subsequently stored primarily in mast cells.
Recognize the two tautomeric forms of histamine and describe the relevance of these forms.Edit
Describe the different types of histamine receptors.Edit
There are 4 types of histamine receptors. All of them are G protein coupled, they differ in their secondary messengers and tissue distribution.
|Receptor Name||Locaion||Action When Stimulated|
|H2||Gastric Parietal Cells in the stomach||gastric acid secretion|
Mainly in the CNS